Indications and Dosage. Intramuscular, Intravenous. Anaerobic infections, Susceptible Gram-positive infections, Susceptible infections. Adult: 600-1,200 mg daily. Severe infections: 1,200-2,700 mg daily, may be increased up to 4,800 mg daily via IV in life-threatening situations. All doses are given in 2-4 equally divided doses.. Reproduction studies performed in rats and mice using oral doses of clindamycin up to 600 mg/kg/day (3.2 and 1.6 times the highest recommended adult human dose based on mg/m 2, respectively) or subcutaneous doses of clindamycin up to 250 mg/kg/day (1.3 and 0.7 times the highest recommended adult human dose based on mg/m 2, respectively.
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Vaginal Suppository: 100 mg #3 Adults: 300mg PO q 6 hours; IV: 600mg to 1200mg/day divided q 12 - 6 hours (1200 to 2700mg/day divided for serious infections); topical: apply to affected area q 12 hours; Intra-vaginal cream: One applicatorful hs for 3 or 7 days (vaginal suppository for 3 days). Children > 10kg: 8-25mg/kg/day PO divided q 8.. 600-1,200 mg per day in 2, 3, or 4 equal doses. which is around 100 mg of clindamycin, into the vagina once daily at bedtime for 3 or 7 consecutive nights.. Pharma Industry / Biotech.
